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Clinical trials that are designed to help inform practice in the real world are referred to as pragmatic trials. They are usually characterized by a focus on the practical aspects of research design, like recruitment and consent as well as adherence to the use of standard equipment.

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Another example of a practical trial is the Home Blood Pressure Management (HBPM) study, which utilized different investigators and included participants from different geographical regions. This type of heterogeneity that is crucial for pragmatic trials to be valid and lessen the chance of bias is also essential. Too much heterogeneity, however could cause issues with the trial design.

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Pragmatic trials aim to mimic real-life settings and achieve maximum external validity. They are usually commissioned by policy makers and practitioners to guide their decision-making. They are also a good method to determine the causal relationship between the intervention and 프라그마틱 무료체험 its effects. However, they shouldn't be used to substitute for the use of explanation trials.

The concept of pragmatism is controversial and there are concerns regarding whether pragmatic trials could be used to replace explanation tests or if they are an addition to them. Schwartz and Lellouch1 suggested a distinction between explanatory trials, which confirm the validity of a clinical or physiological hypothesis and pragmatic trials that inform the policy and practice of. They also proposed the framework for pragmatic trials, dubbed PRECIS.2 This tool sought to define the characteristics of a pragmatic trial which includes the recruitment process, the design and delivery of the intervention, and monitoring.

There is an encouraging increase in the number of pragmatic trials that have been published. A recent Medline search using the terms naturalistic and pragmatic, which was limited to randomized controlled trials (RCTs) produced 34 articles, 프라그마틱 무료 (Http://www.Nzdao.cn/) which are shown in red in Figure 2. This is an indication that the health science community is becoming increasingly sensitized to the subject of pragmatic thinking. It is important to keep in mind that the majority of these studies were conducted in primary-care settings.